Potential Anti-Inflammatory and Anti-Cancer Properties of Farnesol

Potential Anti-Inflammatory and Anti-Cancer Properties of Farnesol

Blog Article

Farnesol, an acyclic sesquiterpene alcohol, is predominantly found in essential oils of various plants in nature.It has been reported to exhibit anti-cancer and anti-inflammatory effects, and also alleviate allergic asthma, gliosis, and edema.In numerous male-chastity tumor cell lines, farnesol can modulate various tumorigenic proteins and/or modulates diverse signal transduction cascades.It can also induce apoptosis and downregulate cell proliferation, angiogenesis, and cell survival.To exert its anti-inflammatory/anti-oncogenic effects, farnesol can modulate Ras protein and nuclear factor kappa-light-chain-enhancer of activated B cells activation to downregulate the expression of various inflammatory mediators such as cyclooxygenase-2, inducible nitric oxide synthase, tumor necrosis factor alpha, and interleukin-6.

In this review, we describe the potential mechanisms of action underlying the therapeutic effects of farnesol against cancers and inflammatory disorders.Furthermore, these findings support the clinical development of farnesol as a potential pharmacological agent in Inkjet Cartridges clinical studies.